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Organic Consultants, Inc.

132 E. Broadway

Suite 107

Eugene, OR 97401

541-484-5971 

CAPABILITIES          

 

CHEMISTRY

We are dedicated to applying our knowledge and experience in organic chemistry to process research with an emphasis on the development of economical, safe, and reproducible synthetic routes for our clients. We have extensive experience in contract research and custom synthesis of:

  • Metabolites

  • Process impurities/ byproducts

  • Degradants

  • Process intermediates

Our areas of expertise include:

  • Alkaloids

  • Heterocycles

  • Terpenes

  • Steroids

  • Prostaglandins

We have seldom been limited in the types of reactions needed to meet our clients’ goals. Our completed projects have included work involving:

  • Chiral syntheses

  • Enzymatic kinetic resolutions

  • Incorporation of stable isotopes into molecular skeletons

  • Pressure reactions (small-scale)

  • Metal-catalyzed carbon-carbon bond formation

  • Hydrogenations (up to several liters)

  • Classical resolutions.

LABORATORIES

Our work is carried out in two organic synthesis laboratories of about 1200 sq. ft. each. Both have a large amount of hood space and standard equipment for organic synthesis, including apparatus for medium pressure hydrogenations, high pressure reactions, and automated flash chromatography. One laboratory is designed for large-scale benchtop reactions (up to 22 liters) for research and synthesis of process intermediates.

Our facilities are equipped with standard analytical instrumentation required  for organic synthesis (low-field NMR,  HPLC, GC, IR, UV-Vis, , etc.)  Additional services (MS, high field NMR, x-ray) are locally accessible.

PERSONNEL

OCI  currently employs six experienced individuals (Five with PhD degrees and one with a BS degree).  Collectively, we have published  nearly 100 journal articles. Included among these are the total synthesis of acorone, uleine, and several 2-acyl indole alkaloids.  We have been co-inventors or sole inventors on numerous patents. 

All employees contribute to the work on every aspect of problems from the design of pathways through the actual preparative chemistry to assembling reports requested by  our clients.

REGULATORY

OCI maintains a research license for Schedule II and III controlled substances. We have over twenty years of continuous experience working with these compounds.

OCI complies with all regulations set by local, state, and federal agencies.

DATA ARCHIVAL

Since the inception of the company, we have and continue to maintain hard and electronic copies of documentation for any and all work.